Changing the Entourage keyboard shortcuts is not a feature of SpamSieve. The shortcut is determined by the name of the file that SpamSieve installs, e.g. “SpamSieve - Train Spam\cmS” where the “\cmS” means “Control-Command-S”. I do not recommend renaming the files. You can, however, override the keyboard shortcuts for any Mac OS X application by going to the Keyboard pane in System Preferences.